Picture of Dr. Lina Marin

Dr. Lina Marin DDS, MSc, PhD, PhD Assistant Professor (On leave)

Address
E3342 HS - 105 Wiggins Road, Saskatoon, SK S7N 5E4

Biography

Dr. Marin obtained her DDS degree from the National University of Colombia in 2007 and has pursued a professional career centred on academia and research. In 2013, she obtained her MSc in Basic Biomedical Sciences from El Bosque University (Colombia), where she worked as an instructor and researcher in cariology until 2014. She then travelled abroad to continue her graduate studies, culminating in receiving two PhD degrees in 2019, a PhD in Dentistry – Cariology conferred by the State University of Campinas, Brazil, and a PhD Biomedical Engineering Sciences – Biomaterials conferred by Western University, Canada. She pursued postdoctoral training at the College of Dentistry, University of Saskatchewan, completing her Postdoctoral Fellowship in 2022. She is currently tenure-track Assistant Professor and course coordinator for Dental Materials courses.

Dr. Marin has received more than 15 awards and honors at the national and international level. In 2014 and 2020, she had the privilege of being selected to present her research at the most prestigious global research competition for oral health trainees, the IADR Hatton Award Competition, representing Colombia in 2014, and Canada in 2020. Dr. Marin has a strong publication record and a wealth of experience in varied laboratory environments integrating basic science with applied clinical research. Her research program focuses on deciphering the dynamic interaction between biofilm-forming microorganisms in the oral cavity and their host to understand the role of the biofilm and the factors and mechanisms involved in health and disease.

Publications

Book Chapters 

  1. Marin LM, Tenuta LM, Tabchoury CPM, Cury JA. Chemical composition and properties of the teeth (in Portuguese). In: Cury JA, Tenuta LMA, Tabchoury CPM, editors. Bioquímica Oral. 3rd ed. São Paulo: Artes Médicas. 2017.

  2. Cury JA, Tenuta LM, Tabchoury CPM, Marin LM. Composition, functions and properties of the saliva (in Portuguese). In: Cury JA, Tenuta LMA, Tabchoury CPM, editors. Bioquímica Oral. 3rd ed. São Paulo: Artes Médicas. 2017.

  1. Tenuta LM, Marin LM, Cury JA. Mechanisms of action of fluoride (in Portuguese). In: Cury JA, Tenuta LMA, Tabchoury CPM, editors. Bioquímica Oral. 3rd ed. São Paulo: Artes Médicas. 2017.

 Peer Reviewed Journal Manuscripts
  1. Gutierrez GM, Marin LM, Xiao Y, Escalante-Herrera A, Santos MT, Siqueira WL. Detection of periodontal disease activity based on histatin degradation in individuals with cerebral palsy. Heliyon 2022;e10134.
  1. Madathil S, Siqueira WL, Marin LM, Sanaulla FB, Faraj N, Quiñonez CR, McNally M, Glogauer M, Allison P. The incidence of COVID-19 among dentists practicing in the community in Canada: A prospective cohort study over a six-month period. J Am Dent Assoc. 2022;153:450-459.e1.
  1. Marin LM, Xiao Y, Cury JA, Siqueira WL. Engineered salivary peptides reduce enamel demineralization provoked by cariogenic mutans biofilm. Microorganisms 2022;10:742.
  1. Marin LM, Xiao Y, Cury JA, Siqueira WL. Modulation of Streptococcus mutans adherence to hydroxyapatite by engineered salivary peptides. Microorganisms 2022;10:223.
  1. Marin LM, Castiblanco GA, Usuga-Vacca MV, Cury JA, Martignon S. Chemically soluble fluoride in toothpastes marketed in Colombia. CES odontol 2021;34:3-14.
  1. Castiblanco GA, Silva-Hermida BC, Opazo G M, Gonzalez-Carrera MC, Avila V, Gamboa LF, Marin LM, Usuga-Vacca M, Cortes A, Cortés-Muñoz F, Ruiz-Carrizosa JA, Martignon S. Distribution pattern of enamel fluorosis severity: What is it telling us about local fluoride exposure? CES odontol 2021;34:15-29.
  1. Marin LM, Cury JA, Siqueira WL. Validation of a cariogenic biofilm model by evaluating the effect of fluoride on enamel demineralization. J Microbiol Methods 2022;192:106386.
  1. Siqueira WL, Canales MP, Crosara KTB, Marin LM, Xiao Y. Proteome difference among the salivary proteins adsorbed onto metallic orthodontic brackets and hydroxyapatite discs. Plos One 2021;16:e0254909.
  1. Caixeta DC, Oliveira SW, Cardoso-Sousa L, Cunha TM, Goulart LR, Martins MM, Marin LM, Jardim ACG, Siqueira WL and Sabino-Silva R. One-Year Update on Salivary Diagnostic of COVID-19. Front Public Health 2021;9:589564.
  1. Zhu Y, Marin LM, Xiao Y, Gillies ER, Siqueira WL. pH-Sensitive Chitosan Nanoparticles for Salivary Protein Delivery. Nanomaterials. 2021;11(4):1028.
  1. Pelissari CVG, Jorge JH, Marin LM, Sabino-Silva R, Siqueira WL. Statherin-derived peptides as antifungal strategy against Candida albicans. Arch Oral Biol 2021;125:105106.
  1. Isho B, Abe KT,  Zuo M,  Jamal AJ,  Rathod B,  Wang JH,  Li Z,  Chao G,  Rojas OL,  Bang YM,  Pu A,  Christie-Holmes N,  Gervais C,  Ceccarelli D,  Samavarchi-Tehrani P,  Guvenc F,  Budylowski P,  Li A,  Paterson A,  Yue FY,  Marin LM,  Caldwell L,  Wrana JL,  Colwill K,  Sicheri F,  Mubareka S,  Gray-Owen SD,  Drews SJ,  Siqueira WL,  Barrios-Rodiles M,  Ostrowski M,  Rini JM,  Durocher Y,  McGeer AJ,  Gommerman JL, Gingras AC. Persistence of serum and saliva antibody responses to SARS-CoV-2 spike antigens in COVID-19 patients. Sci Immunol 2020;5(52).
  1. Almeida LF, Marin LM, Martínez-Mier EA, Cury JA. Fluoride Dentifrice Overcomes the Lower Resistance of Fluorotic Enamel to Demineralization. Caries Res. 2019;53(5):567-575.
  1. Bastidas-Legarda LY, Beltrán EO, Marin-Gallon LM, Castellanos JE, Bohórquez SP. Description of an in vivo oral mucosa HSV-1 infection model in mice. Acta Odontol Latinoam 2017;30(3):109-112.
  1. Marin LM, Vieira, W, Tenuta LMA, Tabchoury CP, Cury JA. Fluoride concentration in toothpastes locally sold in Brazil (in Portuguese). Rev Assoc Paul Cir Dent 2016;70(3):317-322.
  1. Marin LM, Cury JA, Tenuta LMA, Castellanos J, Martignon S. Higher fluorosis severity makes enamel less resistant to demineralization. Caries Res 2016;50(4):407-413.
  1. Martignon S, Castiblanco GA, Cortés A, Marin LM, Gómez SI, Gómez OL, Abad DC, Carrillo GA, Lozano ML, Naranjo MC. Report of a methodology for calibrating examiners in the use of the International Caries Detection and Assessment System (ICDAS) (in Spanish). Univ Odontol 2015; 34(73):21-33.
  1. Marin LM, Castellanos J, Tenuta LMA, Martignon S, Cury JA. Standardization of the biopsy technique for determination of fluoride in dental enamel (in Spanish). Revista Salud Bosque 2015;3(2):9-16.
  1. Martignon S, Marin LM, Pitts N, Jácome-Liévano S. Consensus on domains, formation objectives and contents in cariology for undergraduate dental students in Colombia. Eur J of Dent Educ 2014;18:222-233.
  1. Martignon S, Gomez J, Tellez M, Ruiz JA, Marin LM, Rangel MC. Current cariology education in dental schools in Spanish-speaking Latin American countries. J Dent Educ 2013;77(10):1330-1337.
  1. Castellanos JE, Marin LM, Usuga-Vacca MV, Castiblanco GA, Martignon S. Enamel remineralization under the current understanding of dental caries (in Spanish). Univ Odontol 2013;32(69):49-59.
  1. Bernal LJ, Ávila LV, Marin LM, Casas JA, Bohórquez S del P, Barrientos S, Castellanos JE. Detection of the presence of type 1 Herpes Simplex virus antigen and DNA in human trigeminal ganglia (in Spanish). Univ Odontol 2012;31(66):115-123.
  1. Martignon S, Tellez M, Ruiz JA, Padilla A, Lopez S, Gomez J, Marin LM. Clinical performance of three operative techniques in preschool children in Bogotá: a randomized clinical study (in Spanish). Revista Colombiana de Investigación en Odontología 2010;1(2):202-212.
 
Refereed Abstracts and Conference Presentations

  1. Kolbe RJ, Marin LM, Seth R, Faraj N, Madathil SA, Allison P, Quinonez C, Glogauer M, Siqueira WL, Siqueira MF. Longitudinal Biochemical and Self-Reported Stress/Anxiety in Canadian Dentists Amid COVID-19. AADOCR/CADR Annual Meeting & Exhibition, 2022.

  1. Moraes GS, Zambom CR, Silva GDB, Marin LM, Garrido SS, Ferrari PC, Urban VM, Siqueira WL. Development and characterization of liposomes for the controlled release of therapeutic peptides (in Portuguese). 39° Reunião Anual da Sociedade Brasileira de Pesquisa Odontológica. Braz Oral Res 2021;35(Supp3):PN1318.

  1. Marin LM, Chumala P, Sanche S, Julseth L, Penza E, Skomro R, Siqueira WL, Katselis GS. Detection of Salivary Biomarkers of 2019 Novel Coronavirus Using Mass Spectrometry-based Proteomics. 69th ASMS Conference on Mass Spectrometry and Allied Topics, 2021.

  1. Marin LM, Katselis GS, Chumala P, Siqueira WL. Identification of SARS-CoV-2 proteins in saliva of COVID-19 positive individuals. 2021 IADR General Session & Exhibition. J Dent Res, 100(special issue A):0457.

  1. Sanaulla F, Marin LM, Madathil S, Quinonez C, McNally M, Glogauer M, Allison P, Siqueira WL. Self-Collected Saliva and Courier Service – a Feasible Diagnostic Strategy for COVID-19. 2021 IADR General Session & Exhibition. J Dent Res, 100(special issue A):2459.

  1. Marin LM, Xiao Y, Cury J, Siqueira W. Engineered Salivary Peptides Reduce Enamel Demineralization in Cariogenic Streptococcus mutans 98th IADR General Session & Exhibition. Washington, D.C., USA, 2020. J Dent Res, 99(special issue):2300.

  1. Marin LM, Xiao Y, Seo J, Queiroz D, Siqueira W. Dietary Carbohydrates Modulate Streptococcus mutans Adherence and Bacterial Proteome. 98th IADR General Session & Exhibition. Washington, D.C., USA, 2020. J Dent Res, 99(special issue):395.

  1. Marin LM, Xiao Y, Cury JA, Siqueira WL. Effect of engineered salivary peptides on Streptococcus mutans adherence to the enamel. 97th IADR General Session & Exhibition. Vancouver – Canada, 2019. J Dent Res, 98(special issue):958.

  1. Almeida LF, Marin LM, Martinez-Mier EA, Cury JA. F-Dentifrice Overcomes the Lower Resistance of Fluorotic Enamel to Caries. 97th IADR General Session & Exhibition. Vancouver – Canada, 2019. J Dent Res 2018;98(special issue):2995.

  1. Marin LM, Xiao Y, Cury JA, Siqueira WL. Bioengineered salivary peptides protection of enamel in mutans biofilm. 96th IADR General Session & Exhibition. London – United Kingdom, 2018. J Dent Res, 97(special issue A):2347.

  1. Almeida LF, Marin LM, Martinez-Mier EA, Cury JA. Fluoride Formed on Fluorotic-Enamel Subjected to a pH-Cycling-Regimen Under F-Dentifrice. 47th Annual Meeting & Exhibition of the AADR. Fort Lauderdale – USA, 2018. J Dent Res 2018;97(special issue A):908.

  1. Marin LM, Almeida LF, Cury JA. Reactivity of fluorotic enamel to acidified F-gel (in Portuguese). 34° Reunião Anual da Sociedade Brasileira de Pesquisa Odontológica. Braz Oral Res 2017;31(Supp2):AO0102.

  1. Marin LM, Vieira-Filho W, Tenuta LM, Tabchoury CPM, Cury JA. Accuracy and validity of the determination of fluoride in dentifrices with a specific electrode by the direct technique (in Portuguese). 33° Reunião Anual da Sociedade Brasileira de Pesquisa Odontológica. Braz Oral Res 2016;30(Supp1):AO0090.

  1. Marin LM, Tenuta LM, Tabchoury CPM, Cury JA. Available Fluoride Concentration in Local Toothpastes from Brazilian Regions. 63rd ORCA Congress. Athens – Greece. 2016. Caries Res 2016;50:173.

  1. Cury JA, Marin LM, Barijaona E, Tenuta LM, Tabchoury CPM, Decroix B, Holmgren CJ. Evaluation of Total and Total Soluble Fluoride of Toothpastes from Madagascar. 63rd ORCA Congress. Athens – Greece. 2016. Caries Res 2016;50:174.

  1. Tenuta LM, Dall-Agnol MA, Maia CB, Marin LM, Cury JA. In vivo prolonged retention of fluoride varnish increases reactivity with enamel. 63rd ORCA Congress. Athens – Greece. 2016. Caries Res 2016;50:179.

  1. Marin LM, Tenuta LM, Castellanos JE, Martignon S, Cury JA. Fluoride concentration in enamel and pulpal dentin of fluorosed teeth (in Portuguese). 32° Reunião Anual da Sociedade Brasileira de Pesquisa Odontológica. Braz Oral Res 2015;29(Supp1):AO0083.

  1. Marin LM, Castiblanco GA, Usuga-Vacca M, Cury JA, Martignon S. Fluoride Concentration of the Six Most Sold Toothpaste Brands in Colombia. 62nd ORCA Congress. Brussels – Belgium, 2015. Caries Res 2015;49(4):321-322.

  2. Marin LM, Tenuta LM, Castellanos JE, Martignon S, Cury JA. Relationship between degree of fluorosis and enamel hypomineralization. XIX ABOPREV Meeting. Piracicaba – SP, Brazil. Braz J Oral Sci 2015;14(1):001.

  1. Marin LM, Tenuta LM, Castellanos JE, Martignon S, Cury JA. Composition, mechanical properties and demineralization of fluorosed teeth. 92nd IADR General Session & Exhibition. Cape Town – South Africa, 2014. J Dent Res 2014;93(special issue B):869.

  1. Martignon S, Jácome-Liévano S, Marin LM. Current caries paradigm adoption in Colombian dental schools: Follow-up survey. 92nd IADR General Session & Exhibition. Cape Town – South Africa, 2014. J Dent Res 2014;93(special issue B):189.
  1. Marin LM, Tenuta LM, Castellanos JE, Martignon S, Cury JA. Evaluation of fluoride concentration in enamel and dentin with different severities of dental fluorosis (in Spanish). XXIV Encuentro Nacional de Investigación Odontológica ACFO. San Juan de Pasto, 2013.
  1. Marin LM, Millán LV, Martignon S, Lafaurie G. Evaluation of the erosive potential of hypochlorous acid on dental enamel (in Spanish). XXIV Encuentro Nacional de Investigación Odontológica ACFO. San Juan de Pasto, 2013.
  1. Marin LM, Tenuta LM, Castellanos JE, Martignon S, Cury JA. Fluoride Distribution Pattern Throughout Enamel and Dentine of Fluorotic Teeth. 91st IADR General Session & Exhibition. Seattle – United States, 2013. J Dent Res 2013;92(special issue A):2039.
  1. Martignon S, Marin LM, Lara JS, Douglas GVA, Gamboa LF. A Successful Experience with ICDAS-Training Courses in Colombia (2005-2011). 91st IADR General Session & Exhibition. Seattle – United States, 2013. J Dent Res 2013;92(special issue A):2903.
  1. Nóbrega DF, Vieira-Dantas ED, Romão DA, Velo MMAC, Marin LM, Zura-Almuna MJ, Tabchoury CPM, Tenuta LM, Cury JA. "CaF" Formed on Enamel and Root Dentin by APF-gel Application. 91st IADR General Session & Exhibition. Seattle – United States, 2013. J Dent Res 2013;92(special issue A):3269.
  1. Ochoa EM, Jácome-Liévano S, Otalvaro-Castro GJ, Ruiz JA, Marin LM, Martignon S. Curricular-perspective analysis of opportunities and problematics around the new-caries paradigm in Colombian dental schools. 59th Congress of the European Organisation for Caries Research. Cabo Frio - Brazil, 2012. Caries Res 2012;46:3-3.
  1. Martignon S, Otalvaro-Castro GJ, Ochoa EM, Marin LM, Ruiz JA, Garcia LM, Franco AM, Jacome-Lievano S. Embracing the new caries paradigm among Colombian dental schools. 90th IADR General Session & Exhibition. Iguazu Falls – Brazil, 2012. J Dent Res 2012;91(special issue B):1141.
  1. Jacome-Lievano S, Marin LM, Ochoa EM, Otalvaro-Castro GJ, Ruiz JA, Martignon S. Cariology-teaching in Colombia: Contrast of a workshop and a questionnaire. 90th IADR General Session & Exhibition. Iguazu Falls – Brazil, 2012. J Dent Res 2012;91(special issue B):1140.
  1. Martignon S, Ruiz JA, Rangel MC, Tellez M, Gomez J, Falla S, Marin LM. Current Concepts in Cariology Teaching in Latin America. 58th Congress of the European Organisation for Caries Research. Kaunas - Lithuania, 2011. Caries Res 2011;45:207-208.
  1. Martignon S, Tellez M, Marin LM, Ruiz JA, Padilla A, Qvist V. Operative Treatment Performance and Acceptance by Preschoolers with Early Childhood Caries in Bogotá, Colombia. 57th Congress of the European Organisation for Caries Research. Montpellier – France, 2010. Caries Res 2010; 44:193-194.
  1. Beltran EO, Bastidas LY, Marin LM, Bohorquez SP, Castellanos JE. Experimental in-vivo Herpes infection of Trigeminal Ganglia through oral mucosa. 88th IADR General Session & Exhibition. Barcelona – Spain, 2010. J Dent Res 2010;89 (special issue B):428.
  1. Bernal LJ, Avila LV, Marin LM, Casas A, Bohorquez SP, Castellanos JE, Barrientos, S. HSV-1 antigen, DNA and Latency-Associated-Transcripts in human Trigeminal Ganglia. 88th IADR General Session & Exhibition. Barcelona – Spain, 2010. J Dent Res 2010; 89 (special issue B):4286.
  1. Beltran EO, Bastidas LY, Marin LM, Bohorquez SP, Castellanos JE. Establishment of a murine model of in-vivo infection by HSV-1 through the oral mucosa (in Spanish). XX Encuentro Nacional de Investigación Odontológica ACFO. Montería, 2009.
  1. Marin LM, Prada-Arismendy J, Castellanos JE. Changes in the expression of Oligoadenylate Synthetase 1a and 1b in trigeminal neurons infected with type 1 Herpes Simplex (in Spanish). XVIII Encuentro Nacional de Investigación Odontológica ACFO. Manizales, 2007.
  1. Marin LM, Prada-Arismendy J, Bohorquez SP, Castellanos JE. Changes in Oligoadenylate Synthetase, Protein Kinase R and RNase-L mRNA in Trigeminal Ganglia cultures infected by Herpes Simplex. 2° IADR Latinoamerican Division Meeting. Atibaia – Brazil, 2007. Braz Oral Res 2007;21:348-348.
  1. Marin LM, Prada-Arismendy J, Castellanos JE. Changes in Transcripts of Oligoadenylate Synthetase, Protein Kinase R, and RNasa-L in trigeminal ganglia cultures infected by Herpes Simplex Virus. 45° Annual Meeting of Infectous Diseases Society of America IDSA. San Diego – United States, 2007. 45° Annual Meeting of IDSA, Final Program and Abstracts. Arlington, VA: Infectious Diseases Society of America 2007:168-168.
 
Non-refereed Contributions
  1. Marin LM. Risk Assessment for Early Childhood Caries. Oral Health Dialogue; 2(1):4-7.
  1. Martignon S, Jácome-Liévano S, Marin LM. Consensus on domains, training objectives and contents in cariology for the undergraduate course in dentistry (in Spanish). Global Alliance for a Cavity-Free Future – Colombian Chapter. April 2013.